I can give you advice until I'm blue in the face about which career paths to pursue, how to gussy up your resumé, and how to successfully network. But when we get down to brass tacks, what's most important is not that you listen to me. Do yourself a big favor and promise to always listen to your gut.
Your gut is a trusted friend. It sounds the alarm when an opportunity is either too awesome to pass up or not in your best interest. It kicks in before your brain has had a chance to process and digest data about a project or position and decide whether you should actually pursue it.
It's vital to realize that your gut and your brain may disagree, which can result in your body feeling like it is in the throes of a mixed martial arts battle. Your brain may scream, "Do this! How could you not? This position is prestigious and will provide you with nothing but benefits!" But your gut roars, "Danger, Will Robinson! Do not proceed!" Which do you listen to? It's simple: Always trust your gut.
You don't have to take my word for it. A 1997 study in Science showed that participants in a gambling exercise performed best when they combined reasoning with nonconscious biases—their intuition. "Without the help of such biases, overt knowledge may be insufficient to ensure advantageous behavior," the authors wrote.
Despite this evidence that we should trust our intuition, it can still be challenging. Your gut may fight not only your brain but also your trusted advisers. Your mentors might advocate accepting a position, and your brain wholeheartedly agrees. Yet soon, sometimes ever so subtly, you notice a quiet rumbling in your gut. Soon it simmers and stews and boils over and will only cease when you finally pay attention. The message becomes clear: There is something not right with this opportunity, and you need to dedicate further brain power to analyze it.
Many years ago I spoke with someone in my field about how we might work together. One day she emailed me and suggested we partner on a project. She had landed an assignment with a prestigious enterprise. I had stars in my eyes: "Wow, she chose me!" Then the rub was revealed: She proposed that I would write the first draft, using my data and intimate knowledge. She would add to it, and then after a discussion we would submit the agreed-upon version for publication. She would be listed as first author because she had secured the deal, even though I would be doing the heavy lifting and most of the work would be based on my expertise.
My gut screeched, "Stop! Something's not right!" But my mind responded, "Shut up! This is a fantastic opportunity!" And indeed, I knew that participating would probably benefit my career. Still, my gut churned and bubbled. Tortured by the battle raging between my gut and brain, I turned to a mentor for help. He advised me to take on the project. I still remember sitting in that meeting thinking he was right and yet feeling he was absolutely wrong.
In the end, I chose not to collaborate. As soon as I made the decision, my gut quieted down and settled in for a long hibernation. I was free. And I couldn't have been happier.
Although I might have triumphed from that opportunity, I knew I had made the right decision. Soon after, in a wave of euphoria, new ideas and inspiration came to me. Those innovations would not have been possible if my gut had been clogging the creativity channels in my brain with aches of concern and doubt.
Your gut can be a little tricky to understand, especially if you are early in your career. Over the course of my career, I have sought to study the gut instinct to better comprehend its actions. Here's what I've learned about its nature and behavior:
Most significantly, your gut is your BFF. It has your back. It always wants what's best for you. So whether your gut gently moans, happily or sadly cries, or howls in excruciating pain, listen to it. And when it pushes you to do something, act on it. Your gut knows the truth: You are amazing, and that new experience will only make you more amazing.

About Alaina G. Levine
Alaina G. Levine is an award-winning entrepreneur, STEM career consultant, science journalist, professional speaker, and corporate comedian. Her first book, Networking for Nerds (Wiley, 2015), beat out Einstein for the honor of being named one of the Top 5 Books of 2015 by Physics Today Magazine. As President of Quantum Success Solutions, she is a prolific speaker and writer on career development and professional advancement for engineers and scientists. She has delivered over 700 speeches for clients in the US, Europe, Mexico, Canada, and Africa, and has written over 350 articles in international publications such as Nature, Nature Astronomy, NatureJobs, Science, Scientific American, National Geographic News Watch, and IEEE Spectrum. Levine is also currently authoring two online courses for Oxford University Press on career development and entrepreneurship/commercialization and is a consultant, speaker, and writer for the Lindau Nobel Laureate Meetings. Learn more about Levine.