The IEEE/ACM Transactions on Computational Biology and Bioinformatics is a new quarterly that will publish archival research results related to the algorithmic, mathematical, statistical, and computational methods that are central in bioinformatics and computational biology; the development and testing of effective computer programs in bioinformatics; the development and optimization of biological databases; and important biological results that are obtained from the use of these methods, programs, and databases.

T-ITB publishes basic and applied papers dealing with subjects within the wide spectrum of information technology applications in health, healthcare and biomedicine. Papers must contain original information technology content, defined as development, theoretical analysis, critical evaluation/validation of a new system, and/or model pertinent to healthcare, medicine or biology. Articles describing ethical and legal issues, including safety and security, of implemented systems, and educational issues will also be considered, provided that they represent innovations impacting the application of information technology in biomedicine. Articles that contain original and significant results but do not meet this criterion would not be suitable for publication in T-ITB. In order to guarantee quality control as mandated per IEEE policy on standards for publications, the review and editorial handling of manuscripts is an integral part of the paper submission process.