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Issue No. 04 - July-Aug. (2013 vol. 10)
ISSN: 1545-5963
pp: 897-904
Lishuang Li , Coll. of Comput. Sci. & Technol., Dalian Univ. of Technol., Dalian, China
Wenting Fan , Coll. of Comput. Sci. & Technol., Dalian Univ. of Technol., Dalian, China
Degen Huang , Coll. of Comput. Sci. & Technol., Dalian Univ. of Technol., Dalian, China
ABSTRACT
Biomedical named entity recognition (Bio-NER) is a fundamental step in biomedical text mining. This paper presents a two-phase Bio-NER model targeting at JNLPBA task. Our two-phase method divides the task into two subtasks: named entity detection (NED) and named entity classification (NEC). The NED subtask is accomplished based on the two-layer stacking method in the first phase, where named entities (NEs) are distinguished from nonnamed-entities (NNEs) in biomedical literatures without identifying their types. Then six classifiers are constructed by four toolkits (CRF++, YamCha, maximum entropy, Mallet) with different training methods and integrated based on the two-layer stacking method. In the second phase for the NEC subtask, the multiagent strategy is introduced to determine the correct entity type for entities identified in the first phase. The experiment results show that the presented approach can achieve an F-score of 76.06 percent, which outperforms most of the state-of-the-art systems.
INDEX TERMS
Stacking, Biological system modeling, Training, Proteins, Hidden Markov models, RNA, Computational modeling,bioinformatics, Named entity recognition and classification, two-layer stacking method, multiagent
CITATION
Lishuang Li, Wenting Fan, Degen Huang, "A Two-Phase Bio-NER System Based on Integrated Classifiers and Multiagent Strategy", IEEE/ACM Transactions on Computational Biology and Bioinformatics, vol. 10, no. , pp. 897-904, July-Aug. 2013, doi:10.1109/TCBB.2013.106
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