String Processing and Information Retrieval, International Symposium on (1999)
Sept. 21, 1999 to Sept. 24, 1999
Yuan Gao , IBM T. J. Watson Research Center
Kalai Mathee , University ofTennessee at Memphis
Giri Narasimhan , The University of Memphis
Xuning Wang , Parke-Davis Pharmaceutical Research
We use methods from Data Mining and Knowledge Discovery to design an algorithm for detecting motifs in protein sequences. Based on this approach, we have implemented aprogram called \GYM". The Helix-Turn- Helix Motif was used as a model system on which to test our program. The program was also extended to detect Homeodomain motifs. The detection results for the two motifs compare favorably with existing programs. In addition, the GYM program provides a lot of useful information about a given protein sequence.
Y. Gao, G. Narasimhan, X. Wang and K. Mathee, "Motif Detection in Protein Sequences," String Processing and Information Retrieval, International Symposium on(SPIRE), Cancun, Mexico, 1999, pp. 63.