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International Conference on Nano/Micro Engineered and Molecular Systems (2009)
Shenzhen, China
Jan. 5, 2009 to Jan. 8, 2009
ISBN: 978-1-4244-4629-2
pp: 1065-1068
Ju Seok Lee , The Cell and Molecular Biology Program, the University of Arkansas, Fayetteville, 72701 USA
Joon Jin Song , The Department of Mathematical Sciences, the University of Arkansas, Fayetteville, 72701 USA
Russell Deaton , The Department of Computer Science and Computer Engineering, the University of Arkansas, Fayetteville, 72701 USA
Jin-Woo Kim , The Cell and Molecular Biology Program, the University of Arkansas, Fayetteville, 72701 USA
ABSTRACT
Microarray is one of the most powerful DNA detection systems with multiplexing and high throughput capability. However, the current application of microarray is limited to the preliminary genomic screening of biological samples despite of its excellent potentials for other applications, such as biosensing. This paper addresses microarray's possibilities as sensing device by investigating its limit of detection (LOD) and limit of quantification (LOQ), which are defined as the minimum fluorophore concentration for the liable signal detection. The LOD and LOQ, i.e., detection sensitivity, are key indexes to determine the microarray's applicability as bio/nano sensing device.
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CITATION

Joon Jin Song, Ju Seok Lee, R. Deaton and Jin-Woo Kim, "Exploring the potential of microarray technology for bio/nano sensing," International Conference on Nano/Micro Engineered and Molecular Systems(NEMS), Shenzhen, China, 2009, pp. 1065-1068.
doi:10.1109/NEMS.2009.5068757
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