Three-dimensional Computational Mechanical Analysis for 3-layered Aortic Arch Model under Steady and Unsteady Flow with Fluid-structure Interactions
High Performance Computing and Grid in Asia Pacific Region, International Conference on (2005)
Nov. 30, 2005 to Dec. 3, 2005
Feng Gao , Graduate School of Information Science, Japan
Masahiro Watanabe , Japan Advanced Institute of Science and Technology
Teruo Matsuzawa , Japan Advanced Institute of Science and Technology
Cardiovascular disease is the No. 1 killer in the developed countries and is responsible for millions of deaths and disabilities every year. In cardiovascular biomechanics the fluid-structure interaction within large blood vessel is required to understand the aortic wall tear, aortic dissection and so on. A loosely coupled method was used to study the complex mechanical interaction under steady flow and pulsatile flow in a three-layered aortic arch model. The results showed the impact of steady flow and pulsatile flow, the variations of wall stress along arch portion, and wall stress distribution in three-layered wall. The study provide insight into the biomechanics of aortic dissection: at systolic acceleration phase, the highest normal stress in the media layer may be responsible for the tear and dissection extending into the media layer; at foot entrance flow or diastolic phase, the shear stress might contribute to the dissection in the media near the adventitia layer.
Feng Gao, Masahiro Watanabe, Teruo Matsuzawa, "Three-dimensional Computational Mechanical Analysis for 3-layered Aortic Arch Model under Steady and Unsteady Flow with Fluid-structure Interactions", High Performance Computing and Grid in Asia Pacific Region, International Conference on, vol. 00, no. , pp. 161-169, 2005, doi:10.1109/HPCASIA.2005.95