Design of a Low-voltage Instrumentation Amplifier for Enzyme-Extended-Gate Field Effect Transistor Based Urea Sensor Application
Electronic Design, Test and Applications, IEEE International Workshop on (2002)
Christchurch, New Zealand
Jan. 29, 2002 to Jan. 31, 2002
Wen-Yaw Chung , IChung Yuan Christian University
Mao-Hsiang Yeh , IChung Yuan Christian University
Jia-Chyi Chen , IChung Yuan Christian University
Shen-Kan Hsiung , IChung Yuan Christian University
Dorota G. Pijanowska , Institute of Biocybernetics and Biomedical Engineering, PAS
Wladyslaw Torbicz , Institute of Biocybernetics and Biomedical Engineering, PAS
Jung-Chuan Chou , National Yunlin University of Science and Technology
Tai-Ping Sun , National Chi-Nan University
This paper presents a low-voltage operated instrumentation amplifier design for Enzyme-Extended-Gate Field-Effect Transistor (EEGFET) biosensor signal readout applications. The instrumentation amplifier built by three bulk-driven amplifiers fabricated in a 0.5mm double-poly double-metal CMOS technology and other off-chip resistors has been proved to have a potential application in urea sensor signal sensing. Key parameters of the bulk-driven amplifier and the instrumentation amplifier have been verified for the low-voltage signal readout consideration. The system for urea monitoring has been performed with 1.5V power supply. Experiment results show that the developed instrumentation amplifier has an acceptable sensing response of various urea concentrations in the range of 0.3125 to 240mg/dl.
instrumentation amplifier, bulk-driven amplifier, enzyme, extended-gate field effect transistor, urea concentration
S. Hsiung et al., "Design of a Low-voltage Instrumentation Amplifier for Enzyme-Extended-Gate Field Effect Transistor Based Urea Sensor Application," Electronic Design, Test and Applications, IEEE International Workshop on(DELTA), Christchurch, New Zealand, 2002, pp. 177.