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Computer and Information Technology, International Conference on (2010)
Bradford, West Yorkshire, UK
June 29, 2010 to July 1, 2010
ISBN: 978-0-7695-4108-2
pp: 472-479
Hypothyroidism results from an insufficiency either in the production or/and in the action of the thyroid hormones. Most of the patients in hypothyroidism state must adopt hormonal replacement therapy for all their lives. An intelligent controller model for supplying therapeutic drugs to primary hypothyroidism patients, without the thyroid gland, is investigated in this work. Two multilayer perceptron neural networks are used to predict the concentrations of the hormones TSH and T4 in the blood. The controller, based on a set of production rules, uses these forecasts and the current concentrations of such hormones for calculating the necessary drug dosage to be released. Beyond the controller maintaining such concentrations inside regularity bands, it is also able of preventing abrupt changes on the time evolution of these concentrations.
Intelligent control, neural networks, production rules, thyroid hormones

L. H. Monteiro and L. G. Martins, "A Model of Intelligent Controller for Hypothyroidism Treatment," 2010 IEEE 10th International Conference on Computer and Information Technology (CIT), Bradford, 2010, pp. 472-479.
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