Cluster Computing and the Grid, IEEE International Symposium on (2010)
Melbourne, VIC, Australia
May 17, 2010 to May 20, 2010
Proteomics, the study of all the proteins contained in a particular sample, e.g., a cell, is a key technology in current biomedical research. The complexity and volume of proteomics data sets produced by mass spectrometric methods clearly suggests the use of grid-based high-performance computing for analysis. TOPP and OpenMS are open-source packages for proteomics data analysis, however, they do not provide support for Grid computing. In this work we present a portal interface for high-throughput data analysis with TOPP. The portal is based on Rapid, a tool for efficiently generating standardized port lets for a wide range of applications. The web-based interface allows the creation and editing of user-defined pipelines and their execution and monitoring on a Grid infrastructure. The portal also supports several file transfer protocols for data staging. It thus provides a simple and complete solution to high-throughput proteomics data analysis for inexperienced users through a convenient portal interface.
portal, grid computing, mass spectrometry
S. Gesing, O. Kohlbacher, J. van Hemert, A. Bertsch and J. Koetsier, "TOPP goes Rapid," Cluster Computing and the Grid, IEEE International Symposium on(CCGRID), Melbourne, VIC, Australia, 2010, pp. 598-599.