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2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) (2016)
Shenzhen, China
Dec. 15, 2016 to Dec. 18, 2016
ISBN: 978-1-5090-1612-9
pp: 1864-1868
Jian Yang , Department of Mathematics, Logistical Engineering University, Chongqing, China
Tianhong Wang , School of National Medicine, Chengdu University of TCM, China
Xiaona Shen , Department of Mathematics, Logistical Engineering University, Chongqing, China
Xing Chen , Department of Mathematics, Logistical Engineering University, Chongqing, China
Kehui Zhao , School of National Medicine, Chengdu University of TCM, China
Jing Wang , School of National Medicine, Chengdu University of TCM, China
Yi Zhang , School of National Medicine, Chengdu University of TCM, China
Jing Zhao , Department of Mathematics, Logistical Engineering University, Chongqing, China
Yang Ga , Tibetan Traditional Medical College, Lhasa, China
ABSTRACT
In clinical practice at Tibetan area of China, Traditional Tibetan Medicine formula Wuwei-Ganlu-Yaoyu-Keli(WGYK) is widely added in warm water of bath therapy to treat rheumatoid arthritis (RA). However, its action mechanism is not well interpreted yet. In this study, based on gene expression data from microarray experiments, we apply approaches of network pharmacology to further reveal the action mechanism that WGYK exerts on RA from perspective of protein-protein interactions and pathways. This study may facilitate our understanding of anti-RA effect of WGYK from perspective of network pharmacology.
INDEX TERMS
Biological system modeling, Proteins, Immune system, Irrigation, Birds, Databases
CITATION
Jian Yang, Tianhong Wang, Xiaona Shen, Xing Chen, Kehui Zhao, Jing Wang, Yi Zhang, Jing Zhao, Yang Ga, "Network based study for the anti-rheumatic mechanism of Tibetan medicated-bath therapy", 2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), vol. 00, no. , pp. 1864-1868, 2016, doi:10.1109/BIBM.2016.7822802
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