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2013 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) (2013)
Shanghai, China
Dec. 18, 2013 to Dec. 21, 2013
ISBN: 978-1-4799-1309-1
pp: 48-50
Haiou Li , School of Computer Science and Technology, Soochow University Suzhou, 215006, China
Qiang Lu , School of Computer Science and Technology, Soochow University Suzhou, 215006, China
Rong Chen , School of Computer Science and Technology, Soochow University Suzhou, 215006, China
Lijun Quan , School of Computer Science and Technology, Soochow University Suzhou, 215006, China
Xiaoyan Xia , School of Computer Science and Technology, Soochow University Suzhou, 215006, China
ABSTRACT
Predicting the structure of protein-peptide complexes using computational approaches is a difficult problem whose major challenges are properly dealing with molecular flexibility and conformational changes both of the receptor and ligand. Although significant improvements have been achieved in the modeling of side chains, methods for the backbone flexibility in docking still need improvement. In this study a new method is presented for docking peptide into receptor in a full flexible docking manner. It is a parallel approach that combines all the processes during the docking of a folding peptide with a flexible receptor.
INDEX TERMS
Peptides, Proteins, Color, Protocols, Correlation, Computational modeling, Educational institutions
CITATION

H. Li, Q. Lu, R. Chen, L. Quan and X. Xia, "A protein-peptide docking program with modeling receptor flexible areas," 2013 IEEE International Conference on Bioinformatics and Biomedicine(BIBM), Shanghai, China China, 2013, pp. 48-50.
doi:10.1109/BIBM.2013.6732759
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