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2013 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) (2013)
Shanghai, China
Dec. 18, 2013 to Dec. 21, 2013
ISBN: 978-1-4799-1309-1
pp: 332-335
Xiaoxia Ren , DongZhiMen Hospital Eastern Affiliated To Beijing, University of Chinese Medicine, Beijing, 100700, China
Hongmei Zhou , DongZhiMen Hospital Eastern Affiliated To Beijing, University of Chinese Medicine, Beijing, 100700, China
Jinrui Guo , DongZhiMen Hospital Eastern Affiliated To Beijing, University of Chinese Medicine, Beijing, 100700, China
Yahong Wang , DongZhiMen Hospital, Beijing, 100700, China
Guang Zheng , School of Information Science and Engineering, Technology, Lanzhou University, Lanzhou 730000, Gansu, China
Hongtao Guo , The first affiliated hospital of, Henan University of traditional Chinese medicine, Zhengzhou, 450000, China
Yong Tan , Institute of Basic Research in Clinical Medicine, China, Academy of Chinese Medical Sciences, Dongzhimen, Beijing 100700, China
Jing Yang , Institute of Basic Research in Clinical Medicine, China, Academy of Chinese Medical Sciences, Dongzhimen, Beijing 100700, China
Rongfen Dong , DongZhiMen Hospital Eastern Affiliated To Beijing, University of Chinese Medicine, Beijing, 100700, China
Jinrong Zhang , DongZhiMen Hospital Eastern Affiliated To Beijing, University of Chinese Medicine, Beijing, 100700, China
Zhaoli Cui , DongZhiMen Hospital Eastern Affiliated To Beijing, University of Chinese Medicine, Beijing, 100700, China
Aiping Lv , Institute of Basic Research in Clinical Medicine, China, Academy of Chinese Medical Sciences, Dongzhimen, Beijing 100700, China
Miao Jiang , Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, 100700, China
Yaoxian Wang , Dong Zhi Men Hospitai, Beijing, 100700, China
ABSTRACT
Through several thousands years of clinical research and theoretical thoughts, traditional Chinese medicine (TCM) has accumulated rich experience on hypertension. However, the usage of Chinese herbal medicines (CHMs) in formulae is flexible in TCM clinical practice according to pattern differentiation. So, it is important to get the composition rules of Chinese herbal medicines through literatures. Based on the keyword list of Chinese herbal medicine, through the keyword filtering skill, we got the lists of Chinese herbal medicines. However, for Chinese herbal medicine, they are not only mentioned in the plain format of herb names, but also densely described in the form of formulae. As formulae are composed by Chinese herbal medicines according the theory of traditional Chinese medicine, so it is necessary to filtering them out and de-compose them back into specified Chinese herbal medicines. In this study, take hypertension for example, we explored the composition-rules of Chinese herbal medicines and the network of TCM pattern with them. Networks of TCM patterns and CHMs which are most frequently used in hypertension treatment are built-up and analyzed, some regularities are obtained in treating hypertension from 175011 records of literature. And this method could provide useful help for TCM clinical application and Chinese medicine research.
INDEX TERMS
Hypertension, Blood, Liver, Data mining, Educational institutions, Hospitals, Lungs
CITATION

H. Zhou et al., "Rule-based text mining of traditional Chinese medicine patterns with Chinese herbal medicines and formulae on hypertension," 2013 IEEE International Conference on Bioinformatics and Biomedicine(BIBM), Shanghai, China China, 2013, pp. 332-335.
doi:10.1109/BIBM.2013.6732708
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