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2013 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) (2013)
Shanghai, China
Dec. 18, 2013 to Dec. 21, 2013
ISBN: 978-1-4799-1309-1
pp: 208-211
Ping Wang , Medical College oìShanXi Da Tong Universitity, DaTong, 037009, China
Zhiqi Fan , Futian Hospital of traditional Chinese Medicine, Shenzhen, 518034, China
Ruiqiang Fan , Department of Dermatology of TCM hospital of Guangdong Province, 510120, GuangZhou, China
Haiping Bao , Medical College oìShanXi Da Tong Universitity, DaTong, 037009, China
Zhuangyan Zhu , Medical College oìShanXi Da Tong Universitity, DaTong, 037009, China
Yuhong Yan , Futian Hospital of traditional Chinese Medicine, Shenzhen, 518034, China
ABSTRACT
Objective: to analyze the strain distribution and drug sensitivity of Candida mycoderma isolated from patients with vulvovaginal candidiasis(WC), to provide evidence for clinical rational drug use. Method:119 clinical strains were from patients' leucorrhea sample. Those patients saw a doctor in TCM hospital of Guangdong Province's Gynaecological and Dermatological department. Those clinical strains were detected by Chromagar candida colored culture medium and API / ATB kits, fungus drug sensitivity slab. Result: When it came to strain distribution, candida albicans accounted for 81.51%, Candida glabrata accounted for 15.13%, Candida tropicalis accounted for 1.68%, Candida parapsilosis accounted for 1.68% When it confered to susceptibility test, the susceptibility of strains to amphotericin B was strongest. Conclusion: Candida albicans is the most important pathogenic bacterium of WC. Other kinds of Candida mycoderma are more and more. Widespread usage of fluconazol is responsible for this phenomenon. In clinic, we should pay more attention to susceptibility test and rational use of drug to elevate therapeutic efficacy.
INDEX TERMS
Strain, Sensitivity, Microorganisms, Hospitals, Diseases, Anti-fungal
CITATION

P. Wang, Z. Fan, R. Fan, H. Bao, Z. Zhu and Y. Yan, "Strain distribution and detection of drug sensitivity in 119 cases of vulvovaginal candidiasis," 2013 IEEE International Conference on Bioinformatics and Biomedicine(BIBM), Shanghai, China China, 2013, pp. 208-211.
doi:10.1109/BIBM.2013.6732675
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