Nov. 8, 2000 to Nov. 10, 2000
F.C. Erzen , Dept. of Chem. & Environ. Eng., Illinois Inst. of Technol., Chicago, IL, USA
G. Birol , Dept. of Chem. & Environ. Eng., Illinois Inst. of Technol., Chicago, IL, USA
A. Cinar , Dept. of Chem. & Environ. Eng., Illinois Inst. of Technol., Chicago, IL, USA
Glucose-insulin interaction in an insulin-dependent diabetic patient has been simulated using an overall and a detailed model based on pharmacokinetic diagrams of insulin and glucose. Both models are capable of predicting the blood glucose and insulin levels, total glucose uptake and the renal glucose excretion. The simulator is integrated with a graphical user interface to provide a user-friendly environment. The package may be used to perform virtual experiments with various characteristics, diet and exercise conditions.
graphical user interfaces; diseases; physiological models; digital simulation; medical computing; blood; biochemistry; organic compounds; diabetes mellitus dynamics; glucose-insulin interaction; insulin-dependent diabetic patient; detailed model; overall model; pharmacokinetic diagrams; blood glucose level; blood insulin level; total glucose uptake; renal glucose excretion; user-friendly environment; virtual experiments; diet; exercise conditions
F.C. Erzen, G. Birol, A. Cinar, "Simulation Studies on the Dynamics of Diabetes Mellitus", BIBE, 2000, 13th IEEE International Conference on BioInformatics and BioEngineering, 13th IEEE International Conference on BioInformatics and BioEngineering 2000, pp. 231, doi:10.1109/BIBE.2000.889612