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P2P, Parallel, Grid, Cloud, and Internet Computing, International Conference on (2010)
Fukuoka, Fukuoka Prefecture Japan
Nov. 4, 2010 to Nov. 6, 2010
ISBN: 978-0-7695-4237-9
pp: 326-331
This paper presents and analyzes the data requirements within the clinical trial design process with particular focus on the selection of patients who are eligible to participate in the specified clinical study. The latter comprises an extremely time-consuming process which requires considerable budget and effort, whereas the resulting recruited subjects determine both the success of the clinical study and the validity of the clinical study results significantly. Hence, a novel approach based on Service Oriented Architecture mechanisms and the incorporation of a great number of ontologies enabling the semantic linking between clinical research and clinical care and the interpretation of numerous distributed heterogeneous data sources is presented and analyzed followed by the expected impact of its application in the clinical study design and implementation processes.
clinical trial design, subject recruitment, semantic interoperability
Vassiliki Andronikou, Konstantinos Tserpes, Efstathios Karanastasis, Efthymios Chondrogiannis, Theodora Varvarigou, "Semantically-enabled Intelligent Patient Recruitment in Clinical Trials", P2P, Parallel, Grid, Cloud, and Internet Computing, International Conference on, vol. 00, no. , pp. 326-331, 2010, doi:10.1109/3PGCIC.2010.54
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