Issue No. 06 - November/December (1999 vol. 14)
This paper describes a methodology for building intelligent systems for mining biological sequences. The approach formalizes several key aspects of major bioinformatics systems that provide a functional annotation of newly sequenced genomes. The framework provides a high-level notation for specifying global genome structure, learning mechanisms for discovering genes, associating a function with hypothetical genes, and learning models for regulatory elements.
data mining, machine learning, computational genomics, bioinformatics
S. Kasif, "Datascope: Mining Biological Sequences," in IEEE Intelligent Systems, vol. 14, no. , pp. 38-43, 1999.