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<p>The authors argue for the need to model and analyze biological networks at molecular and cellular levels. They propose a computational toolbox for biologists. Central to their approach is the paradigm of hybrid models in which discrete events are combined with continuous differential equations to capture switching behavior.</p>
Vijay Kumar, Harvey Rubin, Rajeev Alur, George J. Pappas, Max Mintz, Jonathan Schug, Calin Belta, "Modeling and Analyzing Biomolecular Networks", Computing in Science & Engineering, vol. 4, no. , pp. 20-31, January/February 2002, doi:10.1109/5992.976434
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