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<p>Software that has been developed to automate and standardize comparison of 3D images is discussed. The major approaches to image registration are examined. The authors' registration and reconstruction software is described. Studies carried out to determine the relative accuracy of the present registration methods are reported. The main goal of the authors is to improve on commercial SPECT reconstruction algorithms and provide quantification accuracy sufficient for numerical assessment of tracer distribution.</p>

E. L. Kramer et al., "Graphics Applied to Medical Image Registration," in IEEE Computer Graphics and Applications, vol. 11, no. , pp. 20-28, 1991.
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