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Displaying 1-19 out of 19 total
A Combinatorial Perspective of the Protein Inference Problem
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics
By Chao Yang,Zengyou He,Weichuan Yu
Issue Date:November 2013
pp. 1542-1547
In a shotgun proteomics experiment, proteins are the most biologically meaningful output. The success of proteomics studies depends on the ability to accurately and efficiently identify proteins. Many methods have been proposed to facilitate the identifica...
 
Moving Object Detection by Detecting Contiguous Outliers in the Low-Rank Representation
Found in: IEEE Transactions on Pattern Analysis and Machine Intelligence
By Xiaowei Zhou, Can Yang, Weichuan Yu
Issue Date:March 2013
pp. 597-610
Object detection is a fundamental step for automated video analysis in many vision applications. Object detection in a video is usually performed by object detectors or background subtraction techniques. Often, an object detector requires manually labeled ...
 
Multisample aCGH Data Analysis via Total Variation and Spectral Regularization
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics
By Xiaowei Zhou, Can Yang, Xiang Wan, Hongyu Zhao, Weichuan Yu
Issue Date:January 2013
pp. 230-235
DNA copy number variation (CNV) accounts for a large proportion of genetic variation. One commonly used approach to detecting CNVs is array-based comparative genomic hybridization (aCGH). Although many methods have been proposed to analyze aCGH data, it is...
 
HapBoost: A Fast Approach to Boosting Haplotype Association Analyses in Genome-Wide Association Studies
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics
By Xiang Wan, Can Yang, Qiang Yang, Hongyu Zhao, Weichuan Yu
Issue Date:January 2013
pp. 207-212
Genome-wide association study (GWAS) has been successful in identifying genetic variants that are associated with complex human diseases. In GWAS, multilocus association analyses through linkage disequilibrium (LD), named haplotype-based analyses, may have...
 
Peptide Reranking with Protein-Peptide Correspondence and Precursor Peak Intensity Information
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics
By Chao Yang, Zengyou He, Can Yang, Weichuan Yu
Issue Date:July 2012
pp. 1212-1219
Searching tandem mass spectra against a protein database has been a mainstream method for peptide identification. Improving peptide identification results by ranking true Peptide-Spectrum Matches (PSMs) over their false counterparts leads to the developmen...
 
Automatic mitral leaflet tracking in echocardiography by outlier detection in the low-rank representation
Found in: 2012 IEEE Conference on Computer Vision and Pattern Recognition (CVPR)
By Xiaowei Zhou, Can Yang, Weichuan Yu
Issue Date:June 2012
pp. 972-979
Tracking the mitral valve leaflet in an ultrasound sequence is a challenging task because of the poor image quality and fast and irregular leaflet motion. Previous algorithms usually applied standard segmentation methods based on edges, object intensity an...
 
A Partial Set Covering Model for Protein Mixture Identification Using Mass Spectrometry Data
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics
By Zengyou He, Can Yang, Weichuan Yu
Issue Date:March 2011
pp. 368-380
Protein identification is a key and essential step in mass spectrometry (MS) based proteome research. To date, there are many protein identification strategies that employ either MS data or MS/MS data for database searching. While MS-based methods provide ...
 
Multiple Peak Alignment in Sequential Data Analysis: A Scale-Space-Based Approach
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics
By Weichuan Yu, Xiaoye Li, Junfeng Liu, Baolin Wu, Kenneth R. Williams, Hongyu Zhao
Issue Date:July 2006
pp. 208-219
In this paper, we address the multiple peak alignment problem in sequential data analysis with an approach based on the Gaussian scale-space theory. We assume that multiple sets of detected peaks are the observed samples of a set of common peaks. We also a...
 
Aligning Peaks Across Multiple Mass Spectrometry Data Sets Using A Scale-Space Based Approach
Found in: 2005 IEEE Computational Systems Bioinformatics Conference - Workshops
By Weichuan Yu, Xiaoye Li, Hongyu Zhao
Issue Date:August 2005
pp. 126-127
<p>In mass spectrometry (MS) based proteomics research, only the spectral biologically relevant in analysis applications such as biomarker discovery and disease classification. number and locations of peaks in different spectra are very likely to be ...
 
Using Skew Gabor Filter in Source Signal Separation and Local Spectral Multi-Orientation Analysis
Found in: Computer Vision and Pattern Recognition, IEEE Computer Society Conference on
By Weichuan Yu, Gerald Sommer, Kostas Daniilidis
Issue Date:July 2004
pp. 462-469
Responses of Gabor wavelets in the mid-frequency space build a local spectral representation scheme with optimal properties regarding the time-frequency uncertainty principle. However, when using Gabor wavelets we observe a skewness in the mid-frequency sp...
 
Oriented Structure of the Occlusion Distortion: Is It Reliable?
Found in: IEEE Transactions on Pattern Analysis and Machine Intelligence
By Weichuan Yu, Gerald Sommer, Steven Beauchemin, Kostas Daniilidis
Issue Date:September 2002
pp. 1286-1290
<p><b>Abstract</b>—In the energy spectrum of an occlusion sequence, the distortion term has the same orientation as the velocity of the occluding signal. Recent works claimed that this oriented structure can be used to distinguish the occ...
 
Detection and Characterization of Multiple Motion Points
Found in: Computer Vision and Pattern Recognition, IEEE Computer Society Conference on
By Weichuan Yu, Gerald Sommer, Steven Beauchemin, Kostas Daniilidis
Issue Date:June 1999
pp. 1171
The computation of optical flow is a well studied topic in biological and computational vision. However, the existence of multiple motions in dynamic imagery due to occlusion or even transparency still raises challenging questions. In this paper, we propos...
 
Active Contours with Group Similarity
Found in: 2013 IEEE Conference on Computer Vision and Pattern Recognition (CVPR)
By Xiaowei Zhou,Xiaojie Huang,James S. Duncan,Weichuan Yu
Issue Date:June 2013
pp. 2969-2976
Active contours are widely used in image segmentation. To cope with missing or misleading features in images, researchers have introduced various ways to model the prior of shapes and use the prior to constrain active contours. However, the shape prior is ...
 
A Combinatorial Perspective of the Protein Inference Problem
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
By Chao Yang, Weichuan Yu, Zengyou He
Issue Date:November 2013
pp. 1542-1547
In a shotgun proteomics experiment, proteins are the most biologically meaningful output. The success of proteomics studies depends on the ability to accurately and efficiently identify proteins. Many methods have been proposed to facilitate the identifica...
     
Multisample aCGH Data Analysis via Total Variation and Spectral Regularization
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
By Can Yang, Hongyu Zhao, Weichuan Yu, Xiang Wan, Xiaowei Zhou
Issue Date:January 2013
pp. 230-235
DNA copy number variation (CNV) accounts for a large proportion of genetic variation. One commonly used approach to detecting CNVs is array-based comparative genomic hybridization (aCGH). Although many methods have been proposed to analyze aCGH data, it is...
     
HapBoost: A Fast Approach to Boosting Haplotype Association Analyses in Genome-Wide Association Studies
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
By Can Yang, Hongyu Zhao, Qiang Yang, Weichuan Yu, Xiang Wan
Issue Date:January 2013
pp. 207-212
Genome-wide association study (GWAS) has been successful in identifying genetic variants that are associated with complex human diseases. In GWAS, multilocus association analyses through linkage disequilibrium (LD), named haplotype-based analyses, may have...
     
Peptide Reranking with Protein-Peptide Correspondence and Precursor Peak Intensity Information
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
By Can Yang, Chao Yang, Weichuan Yu, Zengyou He
Issue Date:July 2012
pp. 1212-1219
Searching tandem mass spectra against a protein database has been a mainstream method for peptide identification. Improving peptide identification results by ranking true Peptide-Spectrum Matches (PSMs) over their false counterparts leads to the developmen...
     
A Partial Set Covering Model for Protein Mixture Identification Using Mass Spectrometry Data
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
By Zengyou He, Can Yang, Weichuan Yu
Issue Date:March 2011
pp. 368-380
Protein identification is a key and essential step in mass spectrometry (MS) based proteome research. To date, there are many protein identification strategies that employ either MS data or MS/MS data for database searching. While MS-based methods provide ...
     
Multiple Peak Alignment in Sequential Data Analysis: A Scale-Space-Based Approach
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
By Baolin Wu, Hongyu Zhao, Junfeng Liu, Kenneth R. Williams, Weichuan Yu, Xiaoye Li
Issue Date:July 2006
pp. 208-219
In this paper, we address the multiple peak alignment problem in sequential data analysis with an approach based on the Gaussian scale-space theory. We assume that multiple sets of detected peaks are the observed samples of a set of common peaks. We also a...
     
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