Probabilistic Search and Energy Guidance for Biased Decoy Sampling in Ab Initio Protein Structure Prediction
IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
By Amarda Shehu, Kevin Molloy, Sameh Saleh
Issue Date:September 2013
Adequate sampling of the conformational space is a central challenge in ab initio protein structure prediction. In the absence of a template structure, a conformational search procedure guided by an energy function explores the conformational space, gather...