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Displaying 1-14 out of 14 total
Multivariate Hypergeometric Similarity Measure
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics
By Chanchala D. Kaddi,R. Mitchell Parry,May D. Wang
Issue Date:November 2013
pp. 1505-1516
We propose a similarity measure based on the multivariate hypergeometric distribution for the pairwise comparison of images and data vectors. The formulation and performance of the proposed measure are compared with other similarity measures using syntheti...
 
Biological Interpretation of Model-Reference Adaptive Control in a Mass Action Kinetics Metabolic Pathway Model
Found in: Bioinformatics and Biomedicine, IEEE International Conference on
By Chang F. Quo,May D. Wang
Issue Date:November 2011
pp. 265-268
The usefulness of control theory to model robustness in metabolic pathways is limited because controller properties and their implications on pathway regulation are unclear. Using sphingolipid biosynthesis in response to single-gene over expression as a ca...
 
The effect of human genome annotation complexity on RNA-Seq gene expression quantification
Found in: 2012 IEEE International Conference on Bioinformatics and Biomedicine Workshops (BIBMW)
By Po-Yen Wu,John H. Phan,May D. Wang
Issue Date:October 2012
pp. 712-717
Next-generation sequencing (NGS) has brought human genomie research to an unprecedented era. RNA-Seq is a branch of NGS that can be used to quantify gene expression and depends on accurate annotation of the human genome (i.e., the definition of genes and a...
 
Quantitative Comparison of Numerical Solvers for Models of Oscillatory Biochemical Systems
Found in: Computer and Computational Sciences, International Multi-Symposiums on
By Chang Quo, May D. Wang
Issue Date:August 2007
pp. 44-
The goal of this work is to find optimal numerical solvers to study models of biological systems of interest. We report 2 simple rules to select the optimal numerical solver(s) for solving stiff, complex oscillatory systems. Numerical solvers currently use...
 
Development of a Knowledge-Based Multi-Scheme Cancer Microarray Data Analysis System
Found in: Computational Systems Bioinformatics Conference, International IEEE Computer Society
By John H. Phan, Chang F. Quo, Kejiao Guo, Weimin Feng, Geoffrey Wang, May D. Wang
Issue Date:August 2004
pp. 474-475
Comparing genes expressed in normal and diseased states assists the understanding of cancer pathophysiology, detection, prognosis, and therapeutic target study. Many existing expression analysis papers show that microarray data are usually case dependent, ...
   
Hypergeometric Similarity Measure for Spatial Analysis in Tissue Imaging Mass Spectrometry
Found in: Bioinformatics and Biomedicine, IEEE International Conference on
By Chanchala Kaddi,R. Mitchell Parry,May D. Wang
Issue Date:November 2011
pp. 604-607
Tissue imaging mass spectrometry (TIMS) is a data-intensive technique for spatial biochemical analysis. TIMS contributes both molecular and spatial information to tissue analysis. We propose and evaluate a similarity measure, based on the hyper geometric d...
 
Improving Microarray Sample Size Using Bootstrap Data Combination
Found in: Computer and Computational Sciences, International Multi-Symposiums on
By John H. Phan, Richard A. Moffitt, Andrea B. Barrett, May D. Wang
Issue Date:October 2008
pp. 37-44
Microarray technology has enabled us to simultaneously measure the expression of thousands of genes. Using this high-throughput technology, we can examine subtle genetic changes between biological samples and build predictive models for clinical applicatio...
 
Histological Image Feature Mining Reveals Emergent Diagnostic Properties for Renal Cancer
Found in: Bioinformatics and Biomedicine, IEEE International Conference on
By Sonal Kothari,John H. Phan,Andrew N. Young,May D. Wang
Issue Date:November 2011
pp. 422-425
Computer-aided histological image classification systems are important for making objective and timely cancer diagnostic decisions. These systems use combinations of image features that quantify a variety of image properties. Because researchers tend to va...
 
Evaluation of normalization methods for RNA-Seq gene expression estimation
Found in: Bioinformatics and Biomedicine Workshop, IEEE International Conference on
By Po-Yen Wu,John H. Phan,Fengfeng Zhou,May D. Wang
Issue Date:November 2011
pp. 50-57
Statistical inferences on RNA-Seq data, e.g., detecting differential gene expression, are meaningful only after proper normalization. However, there is no consensus for choosing a normalization procedure from among the many existing procedures. We evaluate...
 
A web interface for the quantification of microtubule dynamics
Found in: Bioinformatics and Biomedicine Workshop, IEEE International Conference on
By Koon Yin Kong,Adam I. Marcus,Paraskevi Giaanakakou,May D. Wang
Issue Date:November 2011
pp. 209-214
We propose a web interface that allows researchers to quantify and analyze microtubule confocal images online. Most analyses of microtubule confocal images are performed manually using very simple software or tools. Analysis results are stored locally with...
 
EGOMinor: A Genomics and Proteomics Data Computation and Interpretation System for Biomedical Applications
Found in: Computational Systems Bioinformatics Conference, International IEEE Computer Society
By Weimin Feng, Gaurav Tuteja, May D. Wang
Issue Date:August 2004
pp. 562-563
EGOMiner, stands for Enhanced Gene Ontology mining system, is a CORBA based tool developed for genomic and proteomic data analysis. One key function of EGOMiner is to provide biological data interpretation based on Gene Ontology with quantitative and stati...
   
Volumetric Medical Image Compression and Reconstruction for Interactive Visualization in Surgical Planning
Found in: Data Compression Conference
By Abhirup Patra, May D. Wang
Issue Date:March 2003
pp. 442
No summary available.
   
Multivariate Hypergeometric Similarity Measure
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
By Chanchala D. Kaddi, May D. Wang, R. Mitchell Parry
Issue Date:November 2013
pp. 1505-1516
We propose a similarity measure based on the multivariate hypergeometric distribution for the pairwise comparison of images and data vectors. The formulation and performance of the proposed measure are compared with other similarity measures using syntheti...
     
Chronic Care Continuum (C3): mobile-ready life skills training for adolescents with chronic diseases
Found in: Proceedings of the First ACM Workshop on Mobile Systems, Applications, and Services for Healthcare (mHealthSys '11)
By Alain B. Labrique, Chihwen Cheng, Christopher P. Bonafide, Erika S. Poole, James H. Willig, May D. Wang, Todd H. Stokes
Issue Date:November 2011
pp. 1-2
Consensus guidelines from the American Academy of Pediatrics, American Academy of Family Physicians, and American College of Physicians recommend that physicians begin discussing the process of transitioning from pediatric to adult care with patients aroun...
     
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