The Impact of Multiple Protein Sequence Alignment on Phylogenetic Estimation
IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
By Claude W. dePamphilis, Jim Leebens-Mack, Kevin Beckmann, Li-San Wang, P. Kerr Wall, Tandy Warnow
Issue Date:July 2011
Multiple sequence alignment is typically the first step in estimating phylogenetic trees, with the assumption being that as alignments improve, so will phylogenetic reconstructions. Over the last decade or so, new multiple sequence alignment methods have b...