Improved Multiple Sequence Alignments Using Coupled Pattern Mining
IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
By Chris Bailey-Kellogg, Debprakash Patnaik, K. S. M. Tozammel Hossain, Naren Ramakrishnan, Prateek Jain, Srivatsan Laxman
Issue Date:September 2013
We present alignment refinement by mining coupled residues (ARMiCoRe), a novel approach to a classical bioinformatics problem, viz., multiple sequence alignment (MSA) of gene and protein sequences. Aligning multiple biological sequences is a key step in el...