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Pareto Optimality in Organelle Energy Metabolism Analysis
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics
By Claudio Angione,Giovanni Carapezza,Jole Costanza,Pietro Lio,Giuseppe Nicosia
Issue Date:July 2013
pp. 1032-1044
In low and high eukaryotes, energy is collected or transformed in compartments, the organelles. The rich variety of size, characteristics, and density of the organelles makes it difficult to build a general picture. In this paper, we make use of the Pareto...
 
Pareto Optimality in Organelle Energy Metabolism Analysis
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
By Claudio Angione, Giovanni Carapezza, Giuseppe Nicosia, Jole Costanza, Pietro Lio
Issue Date:July 2013
pp. 1032-1044
In low and high eukaryotes, energy is collected or transformed in compartments, the organelles. The rich variety of size, characteristics, and density of the organelles makes it difficult to build a general picture. In this paper, we make use of the Pareto...
     
Pareto epsilon-dominance and identifiable solutions for BioCAD modeling
Found in: Proceedings of the 50th Annual Design Automation Conference (DAC '13)
By Jole Costanza, Pietro Lió
Issue Date:May 2013
pp. 1-9
We propose a framework to design metabolic pathways in which many objectives are optimized simultaneously. This allows to characterize the energy signature in models of algal and mitochondrial metabolism. The optimal design and assessment of the model is a...
     
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