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Strategy for Naturelike Designer Transcription Factors with Reduced Toxicity
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics
By Christian Bach,Prabir K. Patra,Jani M. Pallis,William B. Sherman,Hassan Bajwa
Issue Date:September 2013
pp. 1340-1343
For clinical applications, the biological functions of DNA-binding proteins require that they interact with their target binding site with high affinity and specificity. Advances in randomized production and target-oriented selection of engineered artifici...
 
Use of Multi Threaded Asynchronous DNA Sequence Pattern Searching Tool to Identifying Zinc-Finger-Nuclease Binding Sites on the Human Genome
Found in: Information Technology: New Generations, Third International Conference on
By Kris Erodula, Christian Bach, Hassan Bajwa
Issue Date:April 2011
pp. 985-991
In this paper we present the development and implementation of a comprehensive interoperable computation tool to assist biomedical researchers to conduct, analyze and interpret experiments on a significantly accelerated pace. Explosion of biological data d...
 
Employing the Intellectual Bandwidth Model to Measure Value Creation in Collaborative Environments
Found in: Hawaii International Conference on System Sciences
By Christian Bach, Salvatore Belardo, Sue R. Faerman
Issue Date:January 2004
pp. 10012b
<p>Nunamaker et al. [1] introduced the intellectual bandwidth (IB) model as a research tool to help decision makers to better understand value creation. Bach et al. [2] used the IB model to map value creation attributes of an information system in a ...
   
Increase of Potential Intellectual Bandwidth in a Scientific Community through Implementation of an End-User Information System
Found in: Hawaii International Conference on System Sciences
By Christian Bach, Salvatore Belardo, Jing Zhang
Issue Date:January 2003
pp. 8b
<p>Qureshi, et al. (2002) [1] presented a case study where they used a framework, the Intellectual Bandwidth Model to measure an organization?s ability to create value. The model consists of two dimensions, information assimilation and collaboration....
   
Strategy for Naturelike Designer Transcription Factors with Reduced Toxicity
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
By Christian Bach, Hassan Bajwa, Jani M. Pallis, Prabir Patra, William Sherman
Issue Date:September 2013
pp. 1340-1343
For clinical applications, the biological functions of DNA-binding proteins require that they interact with their target binding site with high affinity and specificity. Advances in randomized production and target-oriented selection of engineered artifici...
     
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