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Inference of the Genetic Network Regulating Lateral Root Initiation in Arabidopsis thaliana
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
By Charlie Hodgman, Daniele Muraro, Helen Byrne, Ive De Smet, John King, Malcolm Bennett, Michael Wilson, Ute Vob
Issue Date:January 2013
pp. 50-60
Regulation of gene expression is crucial for organism growth, and it is one of the challenges in systems biology to reconstruct the underlying regulatory biological networks from transcriptomic data. The formation of lateral roots in Arabidopsis thaliana i...
     
Parameter Estimation Using Metaheuristics in Systems Biology: A Comprehensive Review
Found in: IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
By Charlie Hodgman, Jianyong Sun, Jonathan M. Garibaldi
Issue Date:January 2012
pp. 185-202
This paper gives a comprehensive review of the application of metaheuristics to optimization problems in systems biology, mainly focusing on the parameter estimation problem (also called the inverse problem or model calibration). It is intended for either ...
     
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