In the knowledge economy era,the organization's existing environment has changed enormously: Innovation becomes the original driving force; knowledge occupies the core position of organizations'resource as strategic resource;the competition of organizations runs to global.In such background,knowledge management as the important sources of the corporations'competition superiority, gradually becomes the focus in enterprise management.On the base of synthetical comment to relevant theories such as knowledge management, organization learning and organization innovation, this article studies organization innovation's connotation,process and mechanism based on knowledge management systematically and thoroughly. It also validates the inner relationship of knowledge management,organization learning and organization innovation through empirical research,as well as organization innovation mechanism based on knowledge management perspective.