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19th International Conference on VLSI Design held jointly with 5th International Conference on Embedded Systems Design (VLSID'06)
Efficient DNA Sensing with Fabricated Silicon Nanopores: Diagnosis Methodology and Algorithms
Hyderabad, India
January 03-January 07
ISBN: 0-7695-2502-4
ASCII Text
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Soumendu Bhattacharya, Vishwanath Natarajan, Abhijit Chatterjee, Sankar Nair, "Efficient DNA Sensing with Fabricated Silicon Nanopores: Diagnosis Methodology and Algorithms," VLSI Design, International Conference on, pp. 729-733, 19th International Conference on VLSI Design held jointly with 5th International Conference on Embedded Systems Design (VLSID'06), 2006.
 
 
BibTex
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@article{ 10.1109/VLSID.2006.80,
author = {Soumendu Bhattacharya and Vishwanath Natarajan and Abhijit Chatterjee and Sankar Nair},
title = {Efficient DNA Sensing with Fabricated Silicon Nanopores: Diagnosis Methodology and Algorithms},
journal ={VLSI Design, International Conference on},
volume = {0},
year = {2006},
issn = {1063-9667},
pages = {729-733},
doi = {http://doi.ieeecomputersociety.org/10.1109/VLSID.2006.80},
publisher = {IEEE Computer Society},
address = {Los Alamitos, CA, USA},
}
 
 
RefWorks Procite/RefMan/Endnote
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TY - CONF
JO - VLSI Design, International Conference on
TI - Efficient DNA Sensing with Fabricated Silicon Nanopores: Diagnosis Methodology and Algorithms
SN - 1063-9667
SP729
EP733
A1 - Soumendu Bhattacharya,
A1 - Vishwanath Natarajan,
A1 - Abhijit Chatterjee,
A1 - Sankar Nair,
PY - 2006
KW - null
VL - 0
JA - VLSI Design, International Conference on
ER -
 
Soumendu Bhattacharya, Georgia Institute of Technology
Vishwanath Natarajan, Georgia Institute of Technology
Abhijit Chatterjee, Georgia Institute of Technology
Sankar Nair, Georgia Institute of Technology
Novel advances in fluidic MEMS sensor/sensor electronics design utilizing silicon nanopores have opened the possibility of accurate and "portable" field diagnosis of DNA molecules. Currently, a DC stimulus is used to "push (translocate)" each molecule through a silicon nanopore and the translocation time of the molecule through the nanopore is used to estimate its length. In this paper, it is shown that polymer transport models, combined with knowledge of the electrical forces exerted on each molecule by application of a (calibrated) stimulus to the sensor electrodes, allows much more fine-grained diagnosis of DNA molecules than it is currently possible. Hence, by proper stimulus design, the efficiency of the DNA sensing using silicon sensors can be improved significantly without incurring any additional hardware overhead.
Citation:
Soumendu Bhattacharya, Vishwanath Natarajan, Abhijit Chatterjee, Sankar Nair, "Efficient DNA Sensing with Fabricated Silicon Nanopores: Diagnosis Methodology and Algorithms," vlsid, pp.729-733, 19th International Conference on VLSI Design held jointly with 5th International Conference on Embedded Systems Design (VLSID'06), 2006
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