Sixth International Conference on Parallel and Distributed Computing Applications and Technologies (PDCAT'05) A Novel Genetic Algorithm for HP Model Protein Folding Dalian, China December 05-December 08 ISBN: 0-7695-2405-2
DOI Bookmark: http://doi.ieeecomputersociety.org/10.1109/PDCAT.2005.31
Determination of the native state of a protein from its amino acid sequence is the goal of protein folding simulations, with potential applications in gene therapy and drug design. To predict a global minimum (GM) structure of a given sequence is a difficult task. A genetic algorithm (GA) is an efficient approach to find lowest-energy conformation for HP lattice model. We have introduced some new operators (symmetric and cornerchange operators) to speed up the searching process and give the result more biology significance. The result shows these new operators improved the success of prediction, compared with standard GA for benchmark HP sequence up to 50 residues
Citation:
Jie Song, Jiaxing Cheng, TingTing Zheng, Junjun mao, "A Novel Genetic Algorithm for HP Model Protein Folding," pdcat, pp.935-937, Sixth International Conference on Parallel and Distributed Computing Applications and Technologies (PDCAT'05), 2005 Usage of this product signifies your acceptance of the Terms of Use. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||