We show that leakage current in VLSI circuits is not only a function of the current state (input combination) of a combinational circuit but also is dependent on the state history (previous input combinations.) As an example application of the transition-dependent leakage model, we extend a known technique for calculating and applying the minimum leakage input vector to a combinational circuit in the standby mode to one which calculates and applies a pair of input vectors to initialize the circuit to the minimum leakage configuration.