In this paper we describe our approach for developing a QoS-aware, dependable execution environment for large-scale distributed stream processing applications. Distributed stream processing applications have strong timeliness and security demands. In particular, we address the following challenges:(1) propose a real-time dependable execution model by extending the component-based execution model with real-time and dependability properties, and (2) develop QoS-aware application composition and adaptation techniques that employ resource management strategies and security policies when discovering and selecting application components. Our approach enables us to develop a distributed stream processing environment that is predictable, secure, flexible, and adaptable.