Sixth International Conference on Intelligent Systems Design and Applications (ISDA'06) Volume 1
Protein 3D HP model folding simulation based on ACO
Jinan, China
October 16-October 18
ISBN: 0-7695-2528-8
DOI Bookmark:
http://doi.ieeecomputersociety.org/10.1109/ISDA.2006.221
The paper presents an approach to optimize the protein 3D HP model conformation with ant colony Optimisation (ACO). A rapid coordinate system transfer matrix according to the "right hand" rule we defined is used to reduce the computing time. A new scheme to solve the problem of folding deadlock is suggested. During the update of pheromone, a new update method with dynamic pheromone is given and three local search method are provided. Using these method, 3D conformation of standard test sequences with very low energy was found.
Citation:
Jie Song, Jiaxing Cheng, Tingting Zheng, "Protein 3D HP model folding simulation based on ACO," isda, vol. 1, pp.410-415, Sixth International Conference on Intelligent Systems Design and Applications (ISDA'06) Volume 1, 2006
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