Most of currently used approaches to data clustering are not qualified to quickly cluster a high-dimensional largescale database This paper is devoted to a novel generalized quantum particle model (GQPM) to data self-organizing clustering. The GQPM approach transforms the data clustering process into a stochastic process of particle motion, collision and quantum entanglement on a particle array. In comparison with the GPM clustering method we have proposed before, the GQPM has much faster speed and higher quality for clustering. GQPM is also characterized by the self-organizing clustering and has advantages in terms of the insensitivity to noise, the quality robustness to clustered data, the learning ability, the suitability for highdimensional multi-shape large-scale data sets. The simulations and comparisons have shown the effectiveness and good performance of the proposed GQPM approach to data clustering.