Presently medical research has experienced a paradigm shift from in vivo to in silico experimentation, a development that relies mostly upon bioinformatics. The key to future commercialization of sequence data from Human Genome Project will be to develop informatics technology that transforms this data into information that is useful for diagnosis and therapy. In this new wave of revolution and commercialization our traditional system of Ayurveda needs renovation. Therefore, modern Ayurveda and Siddha practitioners need training in Ayurinformatics to keep pace with the modern system of medicine.