In this paper we present the methodology for Word Sense Disambiguation based on domain information. Domain is a set of words in which there is a strong semantic relation among the words. The words in the sentence contribute to determine the domain of the sentence. The availability of WordNet domains makes the domain-oriented text analysis possible. The domain of the target word can be fixed based on the domains of the content words in the local context. This approach can be effectively used to disambiguate nouns. We present the unsupervised approach to Word Sense Disambiguation using the WordNet domains. The model determines the domain of the target word and the sense corresponding to this domain is taken as the correct sense. We have used the WordNet domains 3.1.as lexical database.