Searching Similar Modules in Protein Interaction Netwo

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	Similar Articles Articles by Hiroyuki Oka Articles by Masanori Arita

21st International Conference on Data Engineering Workshops (ICDEW'05)

Tokyo, Japan

April 05-April 08

ISBN: 0-7695-2657-8

	ASCII Text	x
	Hiroyuki Oka, Masanori Arita, "Searching Similar Modules in Protein Interaction Netwo," Data Engineering Workshops, 22nd International Conference on, pp. 1158, 21st International Conference on Data Engineering Workshops (ICDEW'05), 2005.

	BibTex	x
	@article{ 10.1109/ICDE.2005.279, author = {Hiroyuki Oka and Masanori Arita}, title = {Searching Similar Modules in Protein Interaction Netwo}, journal ={Data Engineering Workshops, 22nd International Conference on}, volume = {0}, year = {2005}, isbn = {0-7695-2657-8}, pages = {1158}, doi = {http://doi.ieeecomputersociety.org/10.1109/ICDE.2005.279}, publisher = {IEEE Computer Society}, address = {Los Alamitos, CA, USA}, }

	RefWorks Procite/RefMan/Endnote	x
	TY - CONF JO - Data Engineering Workshops, 22nd International Conference on TI - Searching Similar Modules in Protein Interaction Netwo SN - 0-7695-2657-8 SP EP A1 - Hiroyuki Oka, A1 - Masanori Arita, PY - 2005 KW - null VL - 0 JA - Data Engineering Workshops, 22nd International Conference on ER -

Hiroyuki Oka, Grad School of Frontier Sciences, Univ of Tokyo

Masanori Arita, Institute for Advanced Biosciences, Keio University, and PRESTO, JST

DOI Bookmark: http://doi.ieeecomputersociety.org/10.1109/ICDE.2005.279

We developed a new method to search protein networks functionally similar to a given query signal transduction pathway within protein interaction networks. This method consists of two parts: 1) a backtracking search algorithm to find topologically identical subgraphs and 2) a measurement of similarity between proteins by using Gene Ontology [1]. For validation of our method, we implemented a software tool and compared its performance with that of PathBLAST [2] on the search of MAPK signal transduction cascades [3]. The result showed that our software tool has equal or better performance than that of PathBLAST.

Citation:

Hiroyuki Oka, Masanori Arita, "Searching Similar Modules in Protein Interaction Netwo," icdew, pp.1158, 21st International Conference on Data Engineering Workshops (ICDEW'05), 2005

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