Cancer is, after heart disease, one of the major causes of death in the developed world. Cancer statistics make grim reading. One in three people in developed countries will be diagnosed with cancer during their lifetime. The worldwide incidence (number of new cases) is currently 10 million, a figure that is expected to double over the next 15-20 years. It is estimated that over 550,000 people died of cancer in the USA alone in 2002. For women, the incidence of breast cancer is 31% (so that one woman in 9 will be diagnosed during her life), followed by lung (12%) and colorectal (12%). For men, the leading cancer is of the prostate (30%), followed by the lung (14%) and colorectum (11%). Colorectal cancer most often metastasises to the liver or pelvis, both with poor prognosis. The first part of this paper concentrates on colorectal and liver cancer, which have been the major focus of our work over the past two years, primarily on a project carried out jointly with GE Healthcare.