Models and model-based transformations are a key part of effective automated software development approaches. Unfortunately, early enthusiasm for Model Driven Architecture (MDA) has dissipated to the point that many people are openly skeptical of the value of any model-driven approach. This paper argues that to be successful, an MDA approach must be executed in context of a sound Enterprise Architecture providing an integrated business architecture and governance structure that enables an organization to respond to business requirements quickly and appropriately. The paper examines the practical realities of MDA, and provides examples, best practices, and heuristics for achieving success with MDA based on IBM's extensive experiences with MDA tooling and technologies.