We proposed a first person shooter for both hands with multiple mouse devices, which are not used in existing games. Players control their movement and shooting separately using dual guns for both hands. For two-hand usage, we designed a display method for multiple mouse pointers. First, we loaded typical physical driver into the memory and registered our developed multiple mouse device driver instead of the existing MS Windows device driver. We then executed both message loop procedures for Windows mouse event handling and those for multiple mouse event handling. We could display multiple mouse cursor images and utilize both mouse devices separately. After that, a prototype game using both hands was developed for an experimental study.