The aim of the designed system is mainly to develop the environment for grouping and interactive learning mechanism performing on e-schoolbag, which preserves traditional academic mechanisms nowadays in Taiwan and enhances the teaching and learning activities among teachers and students in a digital manner. The system is developed based on the traditional teaching and learning models in order to smoothen the transition from paper-based materials into digital document format in each educational activity, and its foundation is the conviction that students learn more by doing and discussing than by watching and listening. The essence of the developed system lies in increased interaction at all levels for mathematical learning programs, from peer-to-peer discussions to one-on-one communications among students and teachers. With the assistance of the interactive learning system in the e-learning era, we expect that students are able to develop positive, optimistic, creative, and cooperative abilities beyond the confines of traditional learning mechanisms.