With today?s unstoppable rise in technological progression, we have seen a growing abundance of consumer health monitoring products in the openmarket. These devices allow patients to have their health signs monitored unobtrusively in their mobile environment. However, the uptake of these technologies is slow and there is a need for a new paradigm to support the cooperation of healthcare professionals using these technologies. The role of the CSCW approach via agents is to increase awareness and collaboration among patients and medical staff in the health monitoring process. The aim of this paper then, is to present a multi-agent collaborative framework for mobile e-health, based on the computer-supported cooperative work (CSCW) paradigm, along with a discussion on its possible workflow effects.