This minitrack focuses on the role of adoption, implementation, use and evaluation factors and the interaction of these factors at various levels for healthcare system success. Successful innovation with information technology (IT) in healthcare continues to challenge research and practice. Information Technology is seen as an enabler of change in healthcare organizations but (information) technology adoption decisions in healthcare are complex because of the uncertainty of benefits and the rate of change of technology. On a system-level, reimbursement structures, regulations, inter-organizational concerns, and the existence of standards may have an explanatory role. On an organizational level, the previous strategic choices, strategic priorities, size and location of the organization, information assurance, and many other factors may play a role. On a project level, resources, project management, etc. plays a role. Many studies also concentrate on the crucial level of the user at an individual level. It is wise to consider individual related success determinants such as relevance, attitude, requirements and resources. Yet, on this level, we need to learn more about the identification of different adoptercategories in practice and about the role that IT has for various work processes that it may simultaneously touch upon.