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28th Hawaii International Conference on System Sciences (HICSS'95)
Hawaii, USA
January 04-January 07
ISBN: 0-8186-6921-7
ASCII Text
x 
 
M.G. Karpoukhin, B.Y. Kogan, W.J. Karplus, "The application of a massively parallel computer to the simulation of electrical wave propagation phenomena in the heart muscle using simplified models," Hawaii International Conference on System Sciences, pp. 112, 28th Hawaii International Conference on System Sciences (HICSS'95), 1995.
 
 
BibTex
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@article{ 10.1109/HICSS.1995.375345,
author = {M.G. Karpoukhin and B.Y. Kogan and W.J. Karplus},
title = {The application of a massively parallel computer to the simulation of electrical wave propagation phenomena in the heart muscle using simplified models},
journal ={Hawaii International Conference on System Sciences},
volume = {0},
year = {1995},
issn = {1060-3425},
pages = {112},
doi = {http://doi.ieeecomputersociety.org/10.1109/HICSS.1995.375345},
publisher = {IEEE Computer Society},
address = {Los Alamitos, CA, USA},
}
 
 
RefWorks Procite/RefMan/Endnote
x 
 
TY - CONF
JO - Hawaii International Conference on System Sciences
TI - The application of a massively parallel computer to the simulation of electrical wave propagation phenomena in the heart muscle using simplified models
SN - 1060-3425
SP
EP
A1 - M.G. Karpoukhin,
A1 - B.Y. Kogan,
A1 - W.J. Karplus,
PY - 1995
KW - digital simulation; parallel processing; cardiology; muscle; medical computing; medical signal processing; massively parallel computer; electrical wave propagation; heart muscle; simplified models; heart arrhythmia simulation; fibrillation; mathematical models; supercomputers; action potential; depolarization; action potential duration restitution; computational process; 2D spiral waves; premature beat; spiral wave; two dimensional spiral wave
VL - 0
JA - Hawaii International Conference on System Sciences
ER -
 
M.G. Karpoukhin, Dept. of Comput. Sci., California Univ., Los Angeles, CA, USA
B.Y. Kogan, Dept. of Comput. Sci., California Univ., Los Angeles, CA, USA
W.J. Karplus, Dept. of Comput. Sci., California Univ., Los Angeles, CA, USA
The simulation of heart arrhythmia and fibrillation are very important and challenging tasks. The solution of these problems using sophisticated mathematical models is beyond the capabilities of modern supercomputers. To overcome these difficulties, it is proposed to break the whole simulation problem into two tightly coupled stages: generation of the action potential using sophisticated models, and propagation of the action potential using simplified models. The well-known simplified models are compared and modified to bring the rate of depolarization and action potential duration restitution closer to reality. The modified method of lines is used to parallelize the computational process. The conditions for the appearance of 2D spiral waves after the application of a premature beat and the subsequent traveling of the spiral wave inside the simulated tissue are studied.
Index Terms:
digital simulation; parallel processing; cardiology; muscle; medical computing; medical signal processing; massively parallel computer; electrical wave propagation; heart muscle; simplified models; heart arrhythmia simulation; fibrillation; mathematical models; supercomputers; action potential; depolarization; action potential duration restitution; computational process; 2D spiral waves; premature beat; spiral wave; two dimensional spiral wave
Citation:
M.G. Karpoukhin, B.Y. Kogan, W.J. Karplus, "The application of a massively parallel computer to the simulation of electrical wave propagation phenomena in the heart muscle using simplified models," hicss, pp.112, 28th Hawaii International Conference on System Sciences (HICSS'95), 1995
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