Fifth International Conference on Grid and Cooperative Computing Workshops Identifying synergistic transcriptional factors involved in the yeast cell cycle using Microarray and ChIP-chip data Hunan, China October 21-October 23 ISBN: 0-7695-2695-0
DOI Bookmark: http://doi.ieeecomputersociety.org/10.1109/GCCW.2006.54
Knowing the synergistic activities of multiple transcription factors (TFs) is important for revealing the underlying mechanisms of transcription regulation in eukaryotic organisms. Based on the Microarray data and ChIP-chip data, we identified the synergistic TF pairs and triplets involved in the yeast cell cycle. The results indicate that: (1) about one third of the predicted synergistic TF pairs, including five novel pairs undiscovered by previous computational methods, are supported by literature evidences; (2) the cell cycle transcription regulation synergistic TF triplet, FKH2-MCM1-NDD1, has been successfully predicted.
Citation:
Dong He, Dao Zhou, Yanhong Zhou, "Identifying synergistic transcriptional factors involved in the yeast cell cycle using Microarray and ChIP-chip data," gccw, pp.357-360, Fifth International Conference on Grid and Cooperative Computing Workshops, 2006 Usage of this product signifies your acceptance of the Terms of Use. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||