Previous work (J.S. McCaskill et al., 1996; 1997) has shown the power of massively parallel configurable hardware (NGEN) in conjunction with dataflow architectures for the simulation of evolving populations. NGEN is a flexible computer hardware for rapid custom circuit simulation of fine grained physical processes via a massively parallel architecture, e.g. 144 hardware configurable field programmable gate arrays (FPGAs, XC4008, Xilinx). NGEN is optimized to implement dataflow architectures and systolic algorithms for large problems and is confectioned with high speed distributed SRAM, 144*8*256 kBit, 15ns access time, on the chip to chip interconnect. Microconfigurable FPGAs allow a further step to close the gap between micro electronics and biology on the information processing area. A design for a massively parallel microconfigurable computer (POLYP) is presented. It is designed to allow online evolution in hardware with significant locally controllable memory resources. It is also designed for high throughput dataflow applications with large problem size. Additionally, an evolvable interface between high rate measurement devices is provided to allow adaptive processing coupled with real time experimental environments. The computer represents the next logical step towards evolvable hardware interacting with biology beyond the massively parallel computer NGEN.