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2007 Frontiers in the Convergence of Bioscience and Information Technologies
Principal Component Analysis of Infectomes in Human Brain Endothelial Cell after C. neoformans Infection
Jeju Island, Korea
October 11-October 13
ISBN: 978-0-7695-2999-8
ASCII Text
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Ambrose Y. Jong, Luo Feng, Steven H.M Chen, Sheng-He Huang, "Principal Component Analysis of Infectomes in Human Brain Endothelial Cell after <i>C. neoformans</i> Infection," Frontiers in the Convergence of Bioscience and Information Technologies, pp. 274-277, 2007 Frontiers in the Convergence of Bioscience and Information Technologies, 2007.
 
 
BibTex
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@article{ 10.1109/FBIT.2007.134,
author = {Ambrose Y. Jong and Luo Feng and Steven H.M Chen and Sheng-He Huang},
title = {Principal Component Analysis of Infectomes in Human Brain Endothelial Cell after <i>C. neoformans</i> Infection},
journal ={Frontiers in the Convergence of Bioscience and Information Technologies},
volume = {0},
year = {2007},
isbn = {978-0-7695-2999-8},
pages = {274-277},
doi = {http://doi.ieeecomputersociety.org/10.1109/FBIT.2007.134},
publisher = {IEEE Computer Society},
address = {Los Alamitos, CA, USA},
}
 
 
RefWorks Procite/RefMan/Endnote
x 
 
TY - CONF
JO - Frontiers in the Convergence of Bioscience and Information Technologies
TI - Principal Component Analysis of Infectomes in Human Brain Endothelial Cell after <i>C. neoformans</i> Infection
SN - 978-0-7695-2999-8
SP274
EP277
A1 - Ambrose Y. Jong,
A1 - Luo Feng,
A1 - Steven H.M Chen,
A1 - Sheng-He Huang,
PY - 2007
VL - 0
JA - Frontiers in the Convergence of Bioscience and Information Technologies
ER -
 
Cell surface molecule CD44 of human brain microvascular endothelial cells (HBMEC) is the receptor of Cryptococcus neoformans during the infection. We performed microarray analysis and used principle component analysis to examine gene profiles of HBMEC in responses to C. neoformans infection. The CD44 levels increases, peaking at the 4-hour time point and then declined gradually. Seventy genes displayed a similar gene profile. Our results showed a dynamic relationship between pathogen-host interactions. The data is useful for the analysis of invasion mechanism of C. neoformans into HBMEC.
Citation:
Ambrose Y. Jong, Luo Feng, Steven H.M Chen, Sheng-He Huang, "Principal Component Analysis of Infectomes in Human Brain Endothelial Cell after C. neoformans Infection," fbit, pp.274-277, 2007 Frontiers in the Convergence of Bioscience and Information Technologies, 2007
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