2007 Frontiers in the Convergence of Bioscience and Information Technologies Micro-Injection System for Localized Drug Delivery Using Embedded Solid Chemical Propellant Jeju Island, Korea October 11-October 13 ISBN: 978-0-7695-2999-8
DOI Bookmark: http://doi.ieeecomputersociety.org/10.1109/FBIT.2007.110
This paper presents a novel micro-injection system for localized drug delivery using embedded solid chemical propellant, azobisisobutyronitrile (AIBN). This system consists of in-plane type of microneedles, a drug reservoir, a chemical fluid source, a chemical fluid source chamber, and a microheater. The AIBN decomposes and produces nitrogen gas and a free radical at about 70. Using this phenomenon, the AIBN on the microheater generates nitrogen gas by supplying an electrical power, and then the generated nitrogen gas injects a drug in the drug reservoir through the micro channel buried at the microneedles. This micro-injection system injects 2.29 ~ 2.9 µl blue ink during about 6 seconds by supplying 30.4 V and 164 mA. This novel injection system is expected to be applicable to the highly precise biological equipments. Key words: micro-injection, drug delivery, azobisisobutyronitrile (AIBN), microneedles, microheater
Citation:
Jae-won Ban, Kyo-in Koo, Sunkil Park, Gilsub Kim, Dong-il "Dan" Cho, "Micro-Injection System for Localized Drug Delivery Using Embedded Solid Chemical Propellant," fbit, pp.567-571, 2007 Frontiers in the Convergence of Bioscience and Information Technologies, 2007 Usage of this product signifies your acceptance of the Terms of Use. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||