Future information, knowledge and content infrastructures which provide highly automatic support in fulfilling users goals will most likely rely on some form of Grid computing. In combination with Semantic Web technologies and Semantic Web services, this infrastructure will be much enhanced to form the Semantic Grid. Last but not least, one of the major driving forces for the Web and its future derivatives is actual content which can range from multimedia data (with some meta data) to "intelligent objects" i.e. content that itself, can either exhibit behavior or at least, carry semantic information that can (and must) be interpreted by the services of the Semantic Grid. This paper proposes GRISINO, an integrated infrastructure for Semantic Web Services, Intelligent Content Objects and Grid that are brought together in the search for an emerging solution that cope with rapidly increasing demands and complexity of next generation distributed applications.