The availability of large, heterogeneous repositories of electronic documents is increasing rapidly, and the need for flexible, sophisticated document manipulation tools is growing correspondingly. This work presents DOMINUS a system for automated electronic documents processing characterized by the intensive exploitation of intelligent techniques in each step of the process from document acquisition in electronic format to document indexing for categorization and information retrieval purposes. It embeds incremental learning techniques useful in the context of web libraries where documents are acquired in an incremental fashion. Since the system is general and flexible, it can be embedded as a document management engine into many different domain-specific applications. Here, we present the exploitation of the system on the Conference Management domain, and show how DOMINUS can usefully support some of the more critical and knowledge-intensive tasks involved by the organization of a scientific conference.