In the radically changing framework of education and training, the E-studium project (http://e-studium.unipg.it) developed at the University of Perugia, proposes a dynamic and versatile education system, managing effectively the learning process and using new ICT technologies to respond individually to the needs of a wide audience of students disseminated in the country. The organization model is an integrated e-learning system, known as blended e-learning (realized through the course management system Moodle), aiming at a renewal of academic education with a focus on quality of teaching, on support of in-class teaching by on-line services and materials, allowing better use and participation by both full-time and part-time students. Beside students, also academic teachers work as experimental subjects for the technologies implemented. In this work the "E-studium" project is presented showing the different phases of development, implementation and analysis of results including usage.